CSACI position statement: Newer generation H1-antihistamines are safer than first-generation H1-antihistamines and should be the first-line antihistamines for the treatment of allergic rhinitis and urticaria
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منابع مشابه
H1 antihistamines and driving
Driving performances depend on cognitive, psychomotor and perception functions. The CNS adverse effects of some H1 antihistamines can alter the patient ability to drive. Data from studies using standardized objective cognitive and psychomotor tests (Choice Reaction Time, Critical Flicker Fusion. Digital Symbol Substitution Test), functional brain imaging (Positron Emission Tomography, functiona...
متن کاملInteractions of the H1 antihistamines.
An interaction is taken to be the situation in which the administration of a drug or substance induces changes in the pharmacokinetics of another simultaneously administered drug – either increasing or decreasing the plasma concentration of the latter, and thus giving rise to the possibility of adverse reactions [1]. According to the primarily responsible pharmacological mechanism, H 1 antihist...
متن کاملParadoxical exacerbation of chronic urticaria by H1-antihistamines and montelukast.
Histamine is the main mediator of urticaria and H1-receptor antagonists represent the treatment of choice in all patients with chronic urticaria. Leukotriene receptor antagonists as montelukast have also been used in patients with chronic urticaria unresponsive to H1-antihistamines alone. We report a patient with chronic urticaria whose disease was paradoxically exacerbated by H1-antihistamines...
متن کاملUse of second generation H1 antihistamines in special situations.
Antihistamine drugs are one of the therapeutic classes most used at world level, at all ages and in multiple situations. Although in general they have a good safety profile, only the more recent drugs (second generation antihistamines) have been studied specifically with regard to the more important safety aspects. Given the variety of antihistamine drugs, they cannot all be considered equivale...
متن کاملSafety profile of bilastine: 2nd generation H1-antihistamines.
Bilastine is a new H1 antagonist with no sedative side effects, no cardiotoxic effects, and no hepatic metabolism. In addition, bilastine has proved to be effective for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria. Pharmacological studies have shown that bilastine is highly selective for the H1 receptor in both in vivo and in vitro studies, and with no apparent affin...
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ژورنال
عنوان ژورنال: Allergy, Asthma & Clinical Immunology
سال: 2019
ISSN: 1710-1492
DOI: 10.1186/s13223-019-0375-9